Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Caspase-3
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.32nM
Assay Description:
Inhibition of caspase3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-3
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.40nM
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-7
(Homo sapiens (Human))
Washington University
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23.2nM
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-6
(Homo sapiens (Human))
Washington University
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-8
(Homo sapiens (Human))
Washington University
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-1
(Homo sapiens (Human))
Washington University
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-3
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM10341
((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.07E+3nM
Assay Description:
Inhibition of staurosporine induced activation of caspase 3 activation in human Hela cells assessed as hydrolysis of Z-DEVD-R110 substrate by micropl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI