Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Development Center For Biotechnology

US Patent

LigandBDBM447508(3-methoxy-6-((3-methoxy-4-((4-methoxybenzyl)oxy)ph...)Copy SMILESCopy InChI

Affinity DataKi:  275nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
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TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Development Center For Biotechnology

US Patent

LigandBDBM447508(3-methoxy-6-((3-methoxy-4-((4-methoxybenzyl)oxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50: >500nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Development Center For Biotechnology

US Patent

LigandBDBM447508(3-methoxy-6-((3-methoxy-4-((4-methoxybenzyl)oxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:PDGFRβ: Inhibition of PDGFRβ kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditi...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
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TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Development Center For Biotechnology

US Patent

LigandBDBM447508(3-methoxy-6-((3-methoxy-4-((4-methoxybenzyl)oxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:FLT3: Inhibition of FLT3 kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 5 ng ...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI