Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
EC50: 110nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
EC50: 330nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
EC50: 4.40E+3nMAssay Description:Transactivation of human Gal4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
EC50: 210nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair
EC50: 54nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair