Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Riken

Curated by ChEMBL

LigandBDBM50278299(1-(6-(7-chloroquinazolin-4-yloxy)pyridin-3-yl)-3-(...)Copy SMILESCopy InChI

Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of SUMO E1 (unknown origin)-mediated RanGAP1 sumoylation by immunoblotting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaGoogleScholar

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TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
Riken

Curated by ChEMBL

LigandBDBM50278299(1-(6-(7-chloroquinazolin-4-yloxy)pyridin-3-yl)-3-(...)Copy SMILESCopy InChI

Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of recombinant GST-fused SUMO E1 (unknown origin) using RanGAP1 as substrate after 2 hrs by immunoblot analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
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TargetNH(3)-dependent NAD(+) synthetase(Bacillus anthracis)
University Of Alabama At Birmingham

Curated by ChEMBL

LigandBDBM50278299(1-(6-(7-chloroquinazolin-4-yloxy)pyridin-3-yl)-3-(...)Copy SMILESCopy InChI

Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of Bacillus anthracis NAD synthetaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI