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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Procathepsin L
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
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Affinity Data
Ki: 7.20nM
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 26nM
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 43nM
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 62nM ΔG°: -42.8kJ/mole
pH: 5.5 T: 2°C
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 68nM ΔG°: -42.6kJ/mole
pH: 5.5 T: 2°C
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 91nM
Assay Description:
The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <32nM
Assay Description:
Inhibitory activity against recombinant human cathepsin L activity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibitory activity against recombinant human cathepsin S activity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Gnf
Ligand
BDBM19545
((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 372nM
Assay Description:
Inhibitory activity against recombinant human cathepsin K activity using fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI