Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
Ki: 660nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in GH4C1 cells after 1 hr by TopCount method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.42E+4nM
Assay Description:
Inhibition of human ERG expressed in CHO cells by IonWorks assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
EC50: 180nM
Assay Description:
Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.00E+3nM
Assay Description:
Agonist activity at human alpha7 nAChR expressed in CHO cells by whole cell patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
EC50: 126nM
Assay Description:
Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50399293
(CHEMBL2086582)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.40E+3nM
Assay Description:
Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells by whole cell patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI