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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Histone deacetylase 6
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 37nM
Assay Description:
Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Histone deacetylase 8
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
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Affinity Data
IC50: 70nM
Assay Description:
Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 1.16E+3nM
Assay Description:
Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+3nM
Assay Description:
Inhibition of HDAC2 in human HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 8.55E+3nM
Assay Description:
Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
University Of Milan
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 8.70E+3nM
Assay Description:
Inhibition of HDAC in human HeLa cells using BOC-Ac-Lys-AMC as substrate incubated for 4 hrs by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 3.00E+4nM
Assay Description:
Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
University Of Milan
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.26E+4nM
Assay Description:
Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
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Affinity Data
IC50: 3.90E+4nM
Assay Description:
Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 11
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
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Affinity Data
IC50: 7.30E+4nM
Assay Description:
Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.50E+4nM
Assay Description:
Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrate
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.10E+4nM
Assay Description:
Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.90E+4nM
Assay Description:
Inhibition of human HDAC4 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 7
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50293361
(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10E+5nM
Assay Description:
Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI