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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University Of Milan

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of HDAC in human HeLa cells using BOC-Ac-Lys-AMC as substrate incubated for 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University Of Milan

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of human HDAC4 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293361(CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed