Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong First Medical University & Shandong Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong First Medical University & Shandong Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in sf9 insect cells using Boc-Lys(TFA)-AM as substrate incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong First Medical University & Shandong Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong First Medical University & Shandong Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC2 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed