Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Emory University

US Patent

LigandBDBM244058(US9428478, TG6-158)Copy SMILESCopy InChI

Affinity DataIC50:  6.00E+8nMAssay Description:Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails US Patent
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TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Emory University

US Patent

LigandBDBM244058(US9428478, TG6-158)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+10nMAssay Description:Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails US Patent
Copy BDB DOI