Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM561992(BDBM50537618 | US11396496, Compound B0)
Affinity DataIC50:  73nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM561992(BDBM50537618 | US11396496, Compound B0)
Affinity DataIC50:  73nMAssay Description:Inhibition of Keap1 kelch domain to Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM561992(BDBM50537618 | US11396496, Compound B0)
Affinity DataIC50:  73nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide interaction with human recombinant Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli DE3 ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM561992(BDBM50537618 | US11396496, Compound B0)
Affinity DataIC50:  74nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent