Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeutrophil collagenase(Homo sapiens (Human))
Combichem

Curated by ChEMBL

LigandBDBM50130108((R)-5-(4-Acetyl-piperazin-1-yl)-2-[benzo[1,3]dioxo...)Copy SMILESCopy InChI

Affinity DataKi:  9nMAssay Description:Inhibition of MMP-8More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Combichem

Curated by ChEMBL

LigandBDBM50130108((R)-5-(4-Acetyl-piperazin-1-yl)-2-[benzo[1,3]dioxo...)Copy SMILESCopy InChI

Affinity DataKi:  120nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBone morphogenetic protein 1(Homo sapiens (Human))
Combichem

Curated by ChEMBL

LigandBDBM50130108((R)-5-(4-Acetyl-piperazin-1-yl)-2-[benzo[1,3]dioxo...)Copy SMILESCopy InChI

Affinity DataKi:  200nMAssay Description:Ability to inhibit procollagen C-terminal proteinase (PCP) tested in vitroMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI