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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50120422(CHEMBL3617852)
Affinity DataIC50:  61nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction expressed in Escherichia coli BL21 codon plus cells using FITC-beta-DEETGEF-OH ...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50120422(CHEMBL3617852)
Affinity DataIC50:  110nMAssay Description:Binding affinity to the Keap1 (321 to 609 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by surface plasmon resonance assa...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50120422(CHEMBL3617852)
Affinity DataEC50:  29nMAssay Description:Inhibition of Keap1 (unknown origin) interaction to Nrf2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50120422(CHEMBL3617852)
Affinity DataKd:  110nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction by SPR assayMore data for this Ligand-Target Pair