Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL

LigandBDBM50081721(CHEMBL3422341)Copy SMILESCopy InChI

Affinity DataIC50:  2.5nMAssay Description:Inhibition of human CYP1B1 assessed as reduction in 7-ethoxyresorufin O-deethylation activity by fluorescence based EROD assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 1A1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL

LigandBDBM50081721(CHEMBL3422341)Copy SMILESCopy InChI

Affinity DataIC50:  12nMAssay Description:Inhibition of human CYP1A1 assessed as reduction in 7-ethoxyresorufin O-deethylation activity by fluorescence based EROD assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 1A2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL

LigandBDBM50081721(CHEMBL3422341)Copy SMILESCopy InChI

Affinity DataIC50:  19nMAssay Description:Inhibition of human CYP1A2 assessed as reduction in 7-ethoxyresorufin O-deethylation activity by fluorescence based EROD assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI