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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone deacetylase 8(Homo sapiens (Human))
Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564258(CHEMBL4793650)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in sf9 insect cells using Boc-Lys(TFA)-AM as substrate incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564258(CHEMBL4793650)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564258(CHEMBL4793650)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC2 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed