Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL

LigandBDBM50297386(3-(3-(tert-butylthio)-1-(3-(6-methoxypyridin-3-yl)...)Copy SMILESCopy InChI

Affinity DataIC50:  5.5nMAssay Description:Displacement of [3H]3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzyl-indol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL

LigandBDBM50297386(3-(3-(tert-butylthio)-1-(3-(6-methoxypyridin-3-yl)...)Copy SMILESCopy InChI

Affinity DataIC50:  420nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI