Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL

LigandBDBM50297384(3-(3-(tert-butylthio)-1-(4-(5-methoxypyridin-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50:  6.80nMAssay Description:Displacement of [3H]3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzyl-indol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2C9(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL

LigandBDBM50297384(3-(3-(tert-butylthio)-1-(4-(5-methoxypyridin-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50: >10nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL

LigandBDBM50297384(3-(3-(tert-butylthio)-1-(4-(5-methoxypyridin-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50: >10nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI