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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Cephalon
Ligand
BDBM24947
(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)
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Affinity Data
IC50: 55nM
pH: 7.2 T: 2°C
Assay Description:
The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Cephalon
Ligand
BDBM24947
(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)
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Copy InChI
Affinity Data
IC50: 103nM
pH: 7.2 T: 2°C
Assay Description:
The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Cephalon
Ligand
BDBM24947
(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)
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Affinity Data
IC50: 1.27E+3nM
Assay Description:
Compounds were evaluated for their ability to inhibit the kinase activity of TrkA using an ELISA-based assay. The 96-well microtiter plate is coated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 10
(Homo sapiens (Human))
Cephalon
Ligand
BDBM24947
(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)
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Copy InChI
Affinity Data
IC50: 1.58E+3nM
pH: 7.2 T: 2°C
Assay Description:
The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Cephalon
Ligand
BDBM24947
(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)
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Copy InChI
Affinity Data
IC50: 4.72E+3nM
Assay Description:
Compounds were evaluated for their ability to inhibit the kinase activity using an ELISA-based assay. The 96-well microtiter plate is coated with sub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI