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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Irbm/Merck Research Laboratories
Ligand
BDBM25147
(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
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Affinity Data
IC50: 670nM
pH: 8.0 T: 2°C
Assay Description:
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Irbm/Merck Research Laboratories
Ligand
BDBM25147
(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
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Affinity Data
IC50: 880nM
pH: 8.0 T: 2°C
Assay Description:
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Irbm/Merck Research Laboratories
Ligand
BDBM25147
(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
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Affinity Data
IC50: 1.00E+3nM
pH: 8.0 T: 2°C
Assay Description:
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Irbm/Merck Research Laboratories
Ligand
BDBM25147
(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
pH: 8.0 T: 2°C
Assay Description:
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Irbm/Merck Research Laboratories
Ligand
BDBM25147
(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
pH: 8.0 T: 2°C
Assay Description:
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI