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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of human liver CYP1B1 expressed in HEK293 cells using CEC as substrate preincubated for 30 mins followed by substrate addition measured af...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of human liver CYP1B1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate preincubated for 30 mins followed by substrate additi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Effective concentration required against L100I mutant HIV-1 reverse transcriptase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
IC50: 65nM
Assay Description:
Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
IC50: 795nM
Assay Description:
Inhibition of human liver CYP1A1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of human liver CYP1A2 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using CEC as substrate after 10 mins by fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
Inhibition of human liver CYP2D6 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using EOMCC as substrate after 10 mins by fluorescenc...
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Affinity Data
IC50: 1.06E+4nM
Assay Description:
Inhibition of human liver CYP3A4 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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CHEMBL
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human liver CYP2C19 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
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Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human liver CYP2C9 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.30E+3nM
Assay Description:
Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM50236947
(CHEMBL4092737)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.30E+3nM
Assay Description:
In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI