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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 2.40E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay
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Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 5.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay
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Target
Carbonic anhydrase 6
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 5.50E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 5.90E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 8.30E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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Target
Carbonic anhydrase 15
(Mus musculus)
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 8.40E+3nM
Assay Description:
Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
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Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 8.90E+3nM
Assay Description:
Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
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Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 9.00E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay
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Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 9.70E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
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Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 9.80E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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Target
Carbonic anhydrase 3
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: 9.60E+4nM
Assay Description:
Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
Ki: >5.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
Copy SMILES
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Affinity Data
Ki: >5.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
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Target
Aromatase
(Homo sapiens (Human))
Health Sciences University Of Hokkaido
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...
More data for this Ligand-Target Pair
Target Info
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Target
Exportin-1
(Homo sapiens (Human))
Osaka University
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...
More data for this Ligand-Target Pair
Target Info
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
IC50: 6.75E+4nM
Assay Description:
Inhibition human recombinant aldose reductase 1 by spectrophotometric analysis
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Target
Sorbitol dehydrogenase
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
IC50: 1.24E+5nM
Assay Description:
Inhibition sorbitol dehydrogenase by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
Copy SMILES
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Affinity Data
IC50: 1.31E+5nM
Assay Description:
Inhibition of human recombinant aldose reductase using D-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured for ...
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Target
Beta-secretase 1
(Homo sapiens (Human))
Kinki University
Curated by
ChEMBL
Ligand
BDBM50303499
(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
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Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assay
More data for this Ligand-Target Pair
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