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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCytochrome P450 1A2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human CYP1A2 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human CYP1B1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human CYP1A1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human CYP2D6 bound to yeast microsomal membrane using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate after 10 mins by fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C19 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP3A4 bound to yeast microsomal membrane using dibenzylfluorescein as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49471((E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-prope...)
Affinity DataEC50:  1.49E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay