Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50196580(CHEMBL401338 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)Copy SMILESCopy InChI

Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50196580(CHEMBL401338 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)Copy SMILESCopy InChI

Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI