Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50196579(CHEMBL252549 | N-((2S,3R)-4-(3-methoxybenzylamino)...)Copy SMILESCopy InChI

Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50196579(CHEMBL252549 | N-((2S,3R)-4-(3-methoxybenzylamino)...)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI