Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataIC50:  810nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC3 expressed in HEK293F cells in using BML-KI104 as substrate in presence of SAHA as inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using BML-KI104 as substrate in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli using BML-KI178 as substrate and SAHA as inhibitor preincubated for 3 hrs followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using BML-KI104 as substrate in presence of SAHA as inhibitor preincubated for 3 hrs followed by addition of sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC1 expressed in HEK293F cells using BML-KI104 as substrate in presence of SAHA as inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50561977(CHEMBL4752370)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of SAHA and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed