Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sepracor

Curated by ChEMBL

LigandBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)Copy SMILESCopy InChI

Affinity DataIC50:  4.90E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL

LigandBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Sepracor

Curated by ChEMBL

LigandBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI