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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 24 hits in this display   

Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  32.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataKi:  176nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  245nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  790nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  1.82E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(PIG)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  3.47E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  3.47E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C isoform A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  5.25E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  8.91E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  15nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  16nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells co-expressing Galpha16 assessed as decrease in serotonin calcium mobilization ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  34nMAssay Description:In vitro radioligand binding assay on 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  1.39E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  1.88E+3nMAssay Description:In vitro binding affinity towards the alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed