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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universidade De S£O Paulo
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 43.6nM
Assay Description:
Binding affinity to 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 44nM
Assay Description:
Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 105nM
Assay Description:
Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetine
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 500nM
Assay Description:
Affinity of the compound at dopamine D2 receptor, (For haloperidol Ki(nM)= 1.5+/-1.2)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 5.00E+3nM
Assay Description:
Affinity of the compound at 5-hydroxytryptamine 2 receptor (For ketanserin = Ki(nM)= 0.7+/-0.09)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: 5.00E+3nM
Assay Description:
Affinity of the compound at 5-hydroxytryptamine 1D receptor (For sumatriptan = Ki (nM)-12+/-1.9)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102338
(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
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Affinity Data
Ki: >5.00E+3nM
Assay Description:
Affinity of the compound at 5-hydroxytryptamine 3 receptor (For granisetron = Ki (nM)=0.3+/-0.01)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI