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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  19.9nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  19.9nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  150nMAssay Description:Affinity of the compound at dopamine D2 receptor from rat striatum using [3H]-spiroperidol as radioligand (For haloperidol Ki(nM)= 1.5+/-1.2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  250nMAssay Description:Affinity of the compound at 5-hydroxytryptamine 2 receptor from rat frontal cortex using [3H]-ketanserin as radioligand (For ketanserin = Ki(nM)=0.7+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  2.65E+3nMAssay Description:Affinity of the compound at 5-hydroxytryptamine 1D receptor from calf caudate using [3H]-5-HT as radioligand (For sumatriptan = Ki(nM)-12+/-1.9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi: >5.00E+3nMAssay Description:Affinity at 5-hydroxytryptamine 3 receptor from rat frontal cortex using [3H]-granisetron as radioligand (For granisetron = Ki(nM)=0.3+/-0.01)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed