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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: 150nM
Assay Description:
Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetine
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: 180nM
Assay Description:
Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universidade Federal Da Para£Ba
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: 182nM
Assay Description:
Antagonist activity at 5HT1A
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: 1.25E+3nM
Assay Description:
Affinity of the compound at 5-hydroxytryptamine 1D receptor from calf caudate using [3H]-5-HT as radioligand (For sumatriptan = Ki(nM)-12+/-1.9)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: 2.50E+3nM
Assay Description:
Affinity of the compound at dopamine D2 receptor from rat striatum using [3H]-spiroperidol as radioligand (For haloperidol Ki(nM)= 1.5+/-1.2)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: >5.00E+3nM
Assay Description:
Affinity of the compound at 5-hydroxytryptamine 2 receptor from rat frontal cortex using [3H]-ketanserin as radioligand (For ketanserin = Ki(nM)=0.7+...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Universidad De Navarra
Curated by
ChEMBL
Ligand
BDBM50102346
(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
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Affinity Data
Ki: >5.00E+3nM
Assay Description:
Affinity at 5-hydroxytryptamine 3 receptor from rat frontal cortex using [3H]-granisetron as radioligand (For granisetron = Ki(nM)=0.3+/-0.01)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI