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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 0.398nM
Assay Description:
Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 0.400nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
D(2) dopamine receptor
(BOVINE)
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 2.70nM
Assay Description:
Binding affinity of the compound towards D2-dopaminergic receptor using [3H]-NMSP as radioligand
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Target
Serotonin 2 (5-HT2) receptor
(RAT)
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 34nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]DOB as
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 64nM
Assay Description:
Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 225nM
Assay Description:
Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [3H]-mesulergine as radioligand
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 460nM
Assay Description:
Binding affinity of the compound towards 5-hydroxytryptamine 1D receptor using [3H]-5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 890nM
Assay Description:
Binding affinity of the compound towards 5-hydroxytryptamine 1B receptor using [3H]-5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Ligand Info
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In Depth
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Article
PubMed
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Target
D(1A) dopamine receptor
(RAT)
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity of the compound towards Dopamine receptor D1 using [3H]-SCH-23,390 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity of the compound towards 5-hydroxytryptamine 3 receptor using [3H]-GR-65,630 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
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In Depth
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Article
PubMed
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Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Affinity Data
Ki: 1.02E+3nM
Assay Description:
Binding affinity towards beta adrenergic receptor using [3H]DHA as radioligand
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50007170
(Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...)
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Copy InChI
Affinity Data
Kd: 0.400nM
Assay Description:
Inhibition of binding of [125I]-8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI