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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  3.46E+3nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  7.23E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  7.87E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Israel Institution of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  9.90E+4nMMore data for this Ligand-Target Pair
In DepthDetails