Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM228417
(US9556135, 36)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20.2nM
Assay Description:
Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cathepsin D
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM228417
(US9556135, 36)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+5nM
pH: 3.5
Assay Description:
Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI