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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Nuclear receptor corepressor 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544219
(CHEMBL4644575)
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Affinity Data
IC50: 230nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544219
(CHEMBL4644575)
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Affinity Data
IC50: 250nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544219
(CHEMBL4644575)
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Affinity Data
IC50: 700nM
Assay Description:
Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1/2/3/8
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50544219
(CHEMBL4644575)
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Copy InChI
Affinity Data
EC50: 1.70E+4nM
Assay Description:
Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI