Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380740((R)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5...)
BDBM380739(6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)...)
IC50: 120nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380740((R)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5...)
IC50: 136nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380740((R)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5...)
IC50: 220nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380739(6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)...)
IC50: 360nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380739(6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)...)
IC50: 480nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380740((R)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5...)
BDBM380739(6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)...)
IC50: >3.70E+4nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair