Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM264438(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
BDBM264438(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 32nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264438(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 41nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264437(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 65nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264437(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 76nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264437(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 110nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264438(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
BDBM264437(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
IC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair