Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314202((S)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio)-...)Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314202((S)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio)-...)
IC50: 120nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10 fragment after 24 hrs by western blot analysisMore data for this Ligand-Target Pair
Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314200((+/-)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio...)Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314201((R)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio)-...)Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314200((+/-)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio...)
IC50: 493nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10 fragment after 24 hrs by western blot analysisMore data for this Ligand-Target Pair
Cathepsin S(Homo sapiens (Human))Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
BDBM50314201((R)-1-(3-(3-(2-(4-fluoropiperidin-1-yl)ethylthio)-...)
IC50: 810nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of invariant chain p10 fragment after 24 hrs by western blot analysisMore data for this Ligand-Target Pair