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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of JAK2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nuclear receptor corepressor 1
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
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Affinity Data
IC50: 17nM
Assay Description:
Inhibition of human recombinant HDAC3/GST-tagged NCOR1 (397 to 503 residues) co-expressed in insect cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of full length human recombinant HDAC1 expressed in baculovirus expression system using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
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Affinity Data
IC50: 74nM
Assay Description:
Inhibition of full length human recombinant HDAC6 expressed in Baculovirus infected Sf9 cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of TYK2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
Copy SMILES
Copy InChI
Affinity Data
IC50: 76nM
Assay Description:
Inhibition of JAK1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
Copy SMILES
Copy InChI
Affinity Data
IC50: 132nM
Assay Description:
Inhibition of recombinant HDAC2 (unknown origin) using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
Copy SMILES
Copy InChI
Affinity Data
IC50: 144nM
Assay Description:
Inhibition of JAK3 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Second Military Medical University
Curated by
ChEMBL
Ligand
BDBM50361170
(CHEMBL4159366)
Copy SMILES
Copy InChI
Affinity Data
IC50: 572nM
Assay Description:
Inhibition of full length recombinant C-terminal His tagged human HDAC8 expressed in Baculovirus infected Sf9 cells using Ac-Leu-Gly-Lys(Tfa)-AMC as ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI