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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

US Patent
LigandPNGBDBM99644(US8501936, 145)
Affinity DataIC50:  1.55nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

US Patent
LigandPNGBDBM99644(US8501936, 145)
Affinity DataIC50:  43.0nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cephalon

US Patent
LigandPNGBDBM99644(US8501936, 145)
Affinity DataIC50:  671nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In DepthDetails US Patent