Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50272537((2R,3R)-N-[(S)-1-(4-Carbamimidoyl-benzylcarbamoyl)...)Copy SMILESCopy InChI

Affinity DataKi:  42nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50272537((2R,3R)-N-[(S)-1-(4-Carbamimidoyl-benzylcarbamoyl)...)Copy SMILESCopy InChI

Affinity DataKi:  760nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor X(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50272537((2R,3R)-N-[(S)-1-(4-Carbamimidoyl-benzylcarbamoyl)...)Copy SMILESCopy InChI

Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI