Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50483127(Impromidine)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50483127(Impromidine)Copy SMILESCopy InChI

Affinity DataKi:  501nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50483127(Impromidine)Copy SMILESCopy InChI

Affinity DataEC50:  25nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI