Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584284(CHEMBL5086318)
Affinity DataIC50:  83nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured after 24 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584284(CHEMBL5086318)
Affinity DataIC50:  172nMAssay Description:Inhibition of human recombinant DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate and CoQ6 as co-substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584284(CHEMBL5086318)
Affinity DataIC50:  325nMAssay Description:Inhibition of human APC-labeled RORgammat LBD (262 to 518 residues) transfected in Escherichia coli BL21 (DE3) assessed as biotinylated SRC recruitme...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed