Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 9 hits in this display
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: 5.01nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: 9.25nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: >20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: >20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: 250nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
BDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)
IC50: 340nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair