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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50:  7.88nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50:  25nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50: >30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50: >30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50: >30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50:  664nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)
Affinity DataIC50:  720nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent