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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

TargetTrace amine-associated receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50:  2.61E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHistone deacetylase 6(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC2 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC4 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC3 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC7 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC8 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC9 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

Curated by ChEMBL
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC1 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96613(2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phen...)
Affinity DataEC50:  5.94E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay