Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
Omeros
US Patent
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
Ki: <1.00E+3nM
Assay Description:
The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mannan-binding lectin serine protease 2
(Homo sapiens)
Omeros
US Patent
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
Ki: <1.00E+3nM
Assay Description:
The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Coagulation factor XI
(Homo sapiens (Human))
Pcmd
Curated by
PubChem BioAssay
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 49.7nM
pH: 7.4 T: 2°C
Assay Description:
Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Omeros
US Patent
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 949nM
pH: 7.5 T: 2°C
Assay Description:
HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
3C-like protease
(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.34E+3nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Coagulation factor XII
(Homo sapiens (Human))
Pcmd
Curated by
PubChem BioAssay
Ligand
BDBM32909
((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI