Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50314919(1'-(1H-indazole-7-carbonyl)-6,8-dimethylspiro[chro...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL

LigandBDBM50314919(1'-(1H-indazole-7-carbonyl)-6,8-dimethylspiro[chro...)Copy SMILESCopy InChI

Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI