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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 25nM
Assay Description:
Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
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PC sid
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Article
PubMed
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Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 26nM
Assay Description:
Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 61nM
Assay Description:
Inhibition of full length human recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 135nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 350nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human A2780cisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
Copy SMILES
Copy InChI
Affinity Data
IC50: 370nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human Cal27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition meas...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
Copy SMILES
Copy InChI
Affinity Data
IC50: 410nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human Cal27CisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
Copy SMILES
Copy InChI
Affinity Data
IC50: 630nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition meas...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239832
(CHEMBL4090647)
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Affinity Data
IC50: 7.33E+3nM
Assay Description:
Inhibition of eel acetylcholinesterase (AChE) activity by 50%
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI