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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Acyl-CoA:cholesterol acyltransferase
(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acyl-CoA:cholesterol acyltransferase
(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sterol O-acyltransferase 1
(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 75nM
Assay Description:
Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sterol O-acyltransferase 1
(Rattus norvegicus)
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sterol O-acyltransferase 1
(Rattus norvegicus)
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sterol O-acyltransferase 1
(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by
ChEMBL
Ligand
BDBM50051881
(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >500nM
Assay Description:
Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI