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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525704(CHEMBL4574596)
Affinity DataIC50:  843nMAssay Description:Inhibition of recombinant human His-tagged TrkA kinase domain (441-796 residues) expressed in baculovirus expression system incubated with enzyme/ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525704(CHEMBL4574596)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of recombinant full length human TrkA transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525704(CHEMBL4574596)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkB transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed