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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 14nM ΔG°: -44.1kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 29nM ΔG°: -42.3kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Slovak Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 48nM
Assay Description:
Inhibitory activity against human carbonic anhydrase IX
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 60nM
Assay Description:
Inhibitory activity against human carbonic anhydrase II
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 211nM
Assay Description:
Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 250nM ΔG°: -37.1kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze
Ligand
BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
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Affinity Data
Ki: 7.00E+3nM
Assay Description:
Inhibitory activity against human carbonic anhydrase I
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI